Santo Domingo Tonalá is a town and municipality in Oaxaca in south-western Mexico. It is part of the Huajuapan District in the north of the …Santo Domingo Tonalá is a town and municipality in Oaxaca in south-western Mexico. It is part of the Huajuapan District in the north of the Mixteca Region. Santo Domingo Tonala is located about 50 km from Huajuapan de leon.